How USC-led innovation can solve global challenges
Ishwar Puri, USC senior vice president for research and innovation, discusses some of the past year’s major accomplishments and what might be in store for 2023 and beyond.
How old is your brain, really? Artificial intelligence knows
AI-powered analysis developed at USC accurately reflects risk of cognitive decline and Alzheimer’s disease based on brain age.
Study challenges previous ideas regarding Alzheimer’s disease
The buildup of a protein called amyloid beta in the brain, often thought to be connected to Alzheimer’s, may instead be a general change that occurs with age even in healthy brains, USC’s Caleb Finch says.
Unlocking the potential of monoclonal antibodies
Lab-made antibodies are increasingly important in the fight against Alzheimer’s, COVID and other diseases
USC launches large-scale study of dementia and diabetes in adults with Hispanic ancestry
The National Institute on Aging awarded Keck School of Medicine of USC researchers $3.7 million to explore the link between diabetes and brain health in the understudied group.
Fasting-mimicking diet reduces signs of dementia in mice
Short cycles of a low-calorie diet that replicates fasting appeared to reduce inflammation and delay cognitive decline in mouse models of Alzheimer’s disease.
Newly discovered protein connected to Alzheimer’s Disease risk
A mutation in a microprotein is connected to a significant increase in the risk for Alzheimer’s and highlights a possible target for treatment, a USC Leonard Davis School of Gerontology study finds.
What older adults do while they sit affects dementia risk, study indicates
Researchers at USC explored the link between sedentary behavior and risk of dementia, find that type of activity matters when it comes to brain aging.
Willingness to give away money among older adults linked to cognitive profile of early Alzheimer’s
Participants who gave away more money scored significantly lower on cognitive tests known to be sensitive to Alzheimer’s disease than those who gave less, a USC study finds.
USC awarded more than $16 million for research on vascular dysfunction, Alzheimer’s disease
Grant from the National Institute on Aging will fund research on the role that blood vessel dysfunction plays in the development of dementia and Alzheimer’s disease.
Scientists discover genetic variants that speed up and slow down brain aging
The findings could provide potential targets for new Alzheimer’s drugs.
Study finds some of the world’s lowest dementia rates in Amazonian indigenous groups
Research adds to evidence that healthier pre-industrial lifestyles may hold clues to preventing Alzheimer’s and other dementias.
USC endocrinologist takes Alzheimer’s disease research in new directions
By studying the APOE4 gene and its impact on brain inflammation and metabolism of fatty acids, Hussein Yassine discovers potential new ways to prevent cognitive decline.
A brother’s struggle inspires new Alzheimer’s and dementia research collaboration
After watching his twin brother lose a 15-year fight with the memory-robbing illness, Dan Epstein decided to do something about it. The result: an unprecedented research collaboration between USC and UC San Diego.
Study finds older Americans are largely unaware of new Alzheimer’s drug
Among older Americans surveyed in the weeks after FDA approval of aducanumab, few could correctly answer true or false questions about the first new Alzheimer’s drug in decades.
With a $50 million gift, USC and UC San Diego join forces in Alzheimer’s research
A transformative donation from the Epstein Family Foundation will accelerate Alzheimer’s research at the two universities in a push to find better treatments and a cure.
In USC labs, another year of groundbreaking discoveries
Year in review: Whether they’re working with patients, test tubes or massive databases, USC scientists continue to push the envelope with discoveries that are literally changing people’s lives.
Stroke drug shows promise in treating Alzheimer’s and dementia
Mouse study of human stroke medication reveals potential defense against Alzheimer’s disease and other forms of dementia.
How does air pollution influence Alzheimer’s risk?
Studying neural stem cells could shed light on how environmental aspects interact with genetic risk factors for dementia, says University Professor Caleb Finch.
Medications, milestones and disease management: Q&A with Alzheimer’s researcher Lon Schneider
The psychiatry and neuroscience chair at the Keck School of Medicine of USC and director of the California Alzheimer’s Disease Center at USC discusses the role of medication in Alzheimer’s treatment.
USC studies show that clean air matters for a healthy brain
Researchers say their studies on air pollution and cognitive decline — one involving humans and one with mice — provide evidence that cleaner air may reduce risk for Alzheimer’s and other dementias.
Supporting the invisible, unpaid army of Alzheimer’s caregivers
More assistance is needed for the estimated 11 million people caring for loved ones with dementia, USC experts say.
Federal funding for Alzheimer’s multiplies at USC
More than 90 federal grants totaling $92 million were awarded to USC researchers in 2020, underscoring the university’s status as one of the nation’s leading research centers as we acknowledge World Alzheimer’s Day 2021.
Study ties air pollution to disparities in Alzheimer’s risk
Fine particle pollution may be one reason why Black women have double the risk of developing Alzheimer’s than white women, new research from the Keck School of Medicine of USC suggests.